Click on each image below to explore the studies I’ve worked on.
The MOSAICC study is a multi-centre randomised controlled trial evaluating the clinical and cost-effectiveness of intravenous sodium bicarbonate in critically ill patients with metabolic acidosis and acute kidney injury (AKI). It aims to determine whether this treatment can improve outcomes such as mortality at critical care unit discharge, 28 days, and one year.
At the hospital, I primarily contributed to data collection and supported the complex logistics of this study, with one participant recruited before the study closed at our site. This experience deepened my understanding of the challenges involved in critical care research and the importance of meticulous data management.
The UK-ROX study was a large-scale, randomised clinical trial evaluating whether a conservative oxygen therapy strategy (targeting an SpO₂ of 90% ± 2%) improves outcomes compared to usual oxygen therapy in invasively ventilated ICU patients. Oxygen is the most commonly administered drug in critical care, yet the optimal saturation targets remain uncertain. This trial aims to determine the clinical and cost-effectiveness of conservative oxygen therapy, with the primary outcome being all-cause mortality at 90 days.
At the hospital, eligible patients were automatically enrolled into the study, and my primary role involved meticulous data collection to help ensure the integrity and accuracy of the trial’s findings. Contributing to this study deepened my understanding of the nuances of oxygen therapy and its impact on critically ill patients.