Click on each image below to explore the studies I’ve worked on.
The MOSAICC study is a multicentre randomized controlled trial evaluating the clinical and cost-effectiveness of intravenous sodium bicarbonate in critically ill patients with metabolic acidosis and acute kidney injury (AKI). It aims to determine whether this treatment can improve outcomes such as mortality at critical care unit discharge, 28 days, and one year.
At our hospital, I primarily contributed to data collection and supported the complex logistics of this study, with one patient recruited before it closed at our site. This experience deepened my understanding of the challenges in critical care research and the importance of meticulous data management.
The UK-ROX study is a large-scale, randomized clinical trial evaluating whether a conservative oxygen therapy strategy (targeting an SpO₂ of 90% ± 2%) improves outcomes compared to usual oxygen therapy in invasively ventilated ICU patients. Oxygen is the most commonly administered drug in critical care, yet the optimal saturation targets remain uncertain. This trial aims to determine the clinical and cost-effectiveness of conservative oxygen therapy, with the primary outcome being all-cause mortality at 90 days.
At our hospital, patients are automatically enrolled upon meeting eligibility criteria, and my primary role has been meticulous data collection to ensure the integrity and accuracy of the trial's findings. Contributing to this study has deepened my understanding of oxygen therapy's nuances and its impact on critically ill patients.